Principais características dos tumores da parede perivascular de cães: revisão de literatura

Abstract

Perivascular wall tumors (PPT) are cutaneous neoplasms of mesenchymal origin resulting from different non-endothelial cellular components of the vascular wall, such as pericytes, myopericytes, adventitious cells and myofibroblasts. They commonly affect medium and large dogs from middle age to elderly and there is no sexual predilection. It is considered a locally invasive tumor and rarely causes metastases, expressing a benign behavior with potential malignancy. They usually present as solitary, multilobulated, infiltrating tumors, with a grayish white to red color, with a soft or firm consistency, located in the subcutaneous tissue, close to the joints of the limbs, with the thoracic limbs having the highest incidence. This neoplasm has aspects similar to peripheral nerve sheath tumors, being necessary to make the diagnosis by the anatomopathology of the tumor and its distinction from other mesenchymal tumors through immunohistochemistry.