Lúpus eritematoso sistêmico

Abstract

Systemic lupus erythematosus is an immune-mediated disease of unknown etiology that has a genetic predisposition, hormonal and immunological involvement and ultraviolet radiation. The symptoms of the disease are erythema, photosensitivity, oral ulcers, arthritis, weakness, pyrexia, and weight loss, in addition to renal, neurological, hemolytic (anemia, leukopenia and lymphopenia) and immunological (antinuclear antibodies) disorders. Clinical treatment is often a challenge, due to the variety of symptoms that are similar in other dermatological and systemic pathologies; for the development of the diagnosis, the symptoms of the disease, the patient's history and specific tests are necessary.