Aspectos clinico patológicos e alterações laboratoriais do linfoma multicêntrico canino: uma breve revisão de literatura

Abstract

Lymphoma is a neoplasm characterized by proliferation of malignant lymphoid cells, which can develop in any organ, initially affecting lymph nodes, spleen and liver. Its cause is not well understood, but it is believed in multifactorial etiology, genetic factors, immune deficiency and chemical carcinogens. There are four anatomical classifications for lymphoma: multicenter, digestive, mediastinal and extranodal, and 80% of cases in dogs are multicenter lymphomas. The diagnosis is based on cytological, histological and molecular biology analyzes, which help establish the prognosis of the animal considering the degree of lymphoma malignancy and the cell type of origin. Laboratory tests such as hematological and biochemical profile provide data for animal follow-up, disease involvement and staging. In view of the above, it is clear that lymphoma is a very important condition in dogs, and the reduction of the theoretical basis in relation to the clinical presentation of lymphoma is able to establish a successful bridge for both the clinician with alterations capable of generate an early diagnosis, both for the patient regarding their quality of life and survival.