Scrapie

Abstract

Scrapie is a disease that affects sheep and goats caused by an anomalous prion protein that induces the transformation of other normal proteins of the animal to its anomalous isoform form. It belongs to the group of sponiform encephalopathies, which has the characteristic of forming amyloid plaques due to the protein disposition in astrocytic cells, and it is observed that certain genes confer susceptibility or not to this condition.