24° Encontro Acadêmico de Produção Científica do Curso de Medicina Veterinária (ENAVET)

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Subject: search.filters.subject.Neoplasia

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    Osteossarcoma em cães: revisão de literatura
    (Fundação de Ensino Octávio Bastos, 2023-10-18) HONÓRIO, Vinicius M.; CUSTÓDIO, Mariana M.; RODRIGUES, Rafaela F.; GONÇALVES, Brenna M.C. N.
    Osteosarcoma (OSA) is the most common malignant bone neoplasm found in small animal clinics, being locally invasive, rapidly metastatic and aggressive in nature. Histologically it is composed of anaplastic mesenchymal cells that produce osteoid. It generally affects the long bones found in the appendicular skeleton of large dogs.giant size, between 5 and 9 years old, but can also affect bones of the axial skeleton such as ribs, vertebrae, skull and jaw bones. The animal will present with acute or chronic pain, lameness and edema in the affected limb. Due to bone weakness, pathological fractures may occur during the development of the disease. Although the diagnosis of OSA is normally based on clinical history and radiographic findings, histopathological examination and cytology are necessary for more reliable confirmation. To prevent this neoplasm from reaching other regions, it is It is recommended to amputate the affected limb, with a safety margin, associated with chemotherapy or radiotherapy sessions, with the aim of prolonging the animal's life and well-being. To control pain, the use of analgesics and non-steroidal anti-inflammatory drugs can be essential, but in most cases it is necessary to use opioids. The prognosis is generally poor, but will depend on how the animal responds to treatment. The objective of this review is to report on neoplasia in issue, in order to allow you to provide quality of life for the affected dog.
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    Abordagens clinicas e aspectos patológicos relacionados relacionados ao hemangiossarcoma cardíaco em cães: revisão de literatura
    (Fundação de Ensino Octávio Bastos, 2023-10-18) TAGLIAFERRO, Karoline Saturnino; VARGAS, Thiago Henrique Moroni
    Hemangiosarcoma is characterized by being a malignant neoplasm originating from the mesenchymal tissue of endothelial cells, being an important measurement in dogs, as it manifests itself in several organs, including the heart, in a primary or secondary way (through metastasis). In the heart, this disease can be observed in the walls of the right atrium, and, eventually, in the right ventricle. Cardiac hemangiosarcoma may have clinical signs, mainly cardiac tamponade, right heart failure, pericardial effusion and cardiac arrhythmia, however, such signs may vary according to the size of the tumor. In relation to etiopathogenesis and oncogenesis, they have not yet been well clarified, where their origin indicates that they are from bone marrow precursor endothelial cells, and it is also worth highlighting the association with hereditary predisposition. Furthermore, its diagnosis is difficult to conclude, as the changes are not well visualized in exams, such as radiography, laboratory and cytological analyzes of the pericardial fluid, due to the difficult cell differentiation in the effusion. Therefore, definitive diagnosis includes thoracotomy or thoracoscopy, together with biopsy. Regarding treatment, surgical or chemotherapy methods can be taken, such as performing exploratory thoracotomy to resect the tumor mass, respecting safety margins. While chemotherapy includes the interaction of vincristine, doxorubicin and cyclophosphamide, it is more advisable to administer it immediately after the surgical procedure. Therefore, the aim of this work was to highlight and analyze clinical and pathological aspects of this disease, taking into account literary data related to cardiac hemangiosarcoma in dogs.