Browsing by Author "PIROLA, Júlia Cecília"

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    Principais características dos tumores da parede perivascular de cães: revisão de literatura
    (Fundação de Ensino Octávio Bastos, 2022-09-09) PIROLA, Júlia Cecília; PARRA, Pamela Custódio; MATINELLI, Paulo Edson Baptista
    Perivascular wall tumors (PPT) are cutaneous neoplasms of mesenchymal origin resulting from different non-endothelial cellular components of the vascular wall, such as pericytes, myopericytes, adventitious cells and myofibroblasts. They commonly affect medium and large dogs from middle age to elderly and there is no sexual predilection. It is considered a locally invasive tumor and rarely causes metastases, expressing a benign behavior with potential malignancy. They usually present as solitary, multilobulated, infiltrating tumors, with a grayish white to red color, with a soft or firm consistency, located in the subcutaneous tissue, close to the joints of the limbs, with the thoracic limbs having the highest incidence. This neoplasm has aspects similar to peripheral nerve sheath tumors, being necessary to make the diagnosis by the anatomopathology of the tumor and its distinction from other mesenchymal tumors through immunohistochemistry.
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    Síndrome da disfunção cognitiva em cães
    (Centro Universitário da Fundação de Ensino Octávio Bastos, 2019-09-18) PIROLA, Júlia Cecília; FERREIRA, Júlia Eliza; SOUZA, Mariely Thaís de
    Cognitive dysfunction syndrome in dogs (CCDS) is characterized by behavioral changes in geriatric dogs, due to neurodegeneration. The most observed clinical signs are changes in the sleep-wake cycle, gradual cognitive loss with sensory deficits, changes in learning ability, memory, spatial notions, social interactions and decrease in normal daily activities. The prevalence of this disease can happen from the age of six, when the animal begins to show discrete signs of cognitive dysfunction, however, the most evident changes start from 11 years of age. In the diagnosis, in addition to observing behavioral changes suggestive of CCDS, several complementary exams are indicated, such as blood count, serum biochemistry and hormonal tests, ruling out the influence of diseases that can lead to neurological changes such as diabetes, hypothyroidism, renal failure, among others; the definitive diagnosis is obtained by histopathological examination of the nervous tissue, obtained by biopsy in vivo or, in general, in the post-mortem period. The treatment consists of preventing the advance of the neurodegenerative process and restoring the concentrations of neurotransmitters.