Browsing by Author "HUCKE, Erica Elgelberg da Silva"

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Avaliação dos efeitos da Buprenorfina sobre a anestesia induzida pela associação de Quetamina e Xilazina em ratos
(Fundação de Ensino Octávio Bastos, 2004-09-30) SOUZA, Fernanda C.; HUCKE, Erica Elgelberg da Silva; MASSONE, Flávio
The study of anesthetic techniques in rodents has gained increasing importance both for research and veterinary clinic. Therefore, the objective of the present study was to evaluate the possible contribution of buprenorphine in the anesthetic association xylazine plus ketamine in rats. After evaluating the parameters used in the induction, maintenance and recovery periods, it was demonstrated that the use of opioids led to a surgical plan of greater quality and safety, and this type of association is recommended.
Efeito do Diazepam sobre a resposta comportamental ao estresse em ratas nulíparas e primíparas
(Centro Universitário da Fundação de Ensino Octávio Bastos, 2008-11-30) GARCIA, Claudia Fernanda Ribeiro; HUCKE, Erica Elgelberg da Silva
The reproductive experience (ER), that is, the set of pregnancy, childbirth and lactation, is associated with changes in hormone secretion, reducing, for example, steroids and prolactin, possibly for the rest of a female's life. It has been shown that responses to stress are related to the behavioral expression of anxiety in the elevated plus-maze, since stress has an anxiogenic effect in this experimental model, and that both responses to stress and anxiety can be permanently modified according to the RE. In addition, it has been previously demonstrated that the sensitivity of primiparous females to stress can be reduced. Thus, this research project aims to continue previous studies in our laboratory about RE and its relationship with anxiety and stress, by studying the behavior of rats in the elevated plus-maze, evaluating the effect of diazepam.
Efeito do estresse agudo sobre a secreção de prolactina em ratas nulíparas e primíparas
(Centro Universitário da Fundação de Ensino Octávio Bastos, 2008-11-30) ALVISI, Renato Duarte; HUCKE, Erica Elgelberg da Silva
Prolactin is an important hormone responsible for the development of the mammary glands during pregnancy and for the production of milk during the postpartum period. It has been concluded through several studies that the production of prolactin can suffer interference from various stressors, thus resulting in increased production. Physiological factors such as reproductive experience also have an influence on prolactin, but they act in a way to decrease its production. In recent studies carried out on adrenalectomized rats, we observed that the modulation of prolactin secretion exerted by adrenal glucocorticoids does not have the same modulatory effect as a function of reproductive experience, thus indicating that primiparous females would not be as sensitive as nulliparous females to circulating levels of glucocorticoids, which could be suggestive less stress sensitivity. Other experiments carried out with nulliparous and primiparous rats on the influence of acute and prolonged stress on prolactin secretion showed that the reproductive experience does not seem to modify the serum prolactin concentration in response to acute and prolonged stress. However, the acute response could have occurred in less than an hour, the objective of this study being to study the secretion and concentrations of prolactin during the first hour after stimulation of acute stress in primiparous and nulliparous rats.